Prevagen’s featured ingredient is apoaequorin, a protein first discovered in jellyfish. For the most useful answer, separate the label from the bigger memory question: a 90-day company-funded study of 218 adults found no statistically significant result across the full study group, while a smaller follow-up subgroup analysis found differences on selected tests.
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Memory changes can also connect to sleep, stress, hearing or vision changes, and pills. The National Institute on Aging says a medication review can help identify medicines that affect memory, sleep, or brain function. That is a practical first step when you are sorting out supplements and safety at home.
What are the Prevagen ingredients?
Prevagen says apoaequorin is its unique ingredient. Its brand page describes it as a protein originally discovered in jellyfish and now made through a controlled scientific process.
The National Institutes of Health Dietary Supplement Label Database preserves an older, off-market Prevagen Professional label entered in 2013. It listed one capsule with 40 mg apoaequorin and 20 mg sodium. Its other ingredients were white rice flour, salt, magnesium stearate, acetic acid, and disodium EDTA. That archived Professional product was marked off market in 2021, so do not use that label to identify today’s Regular or Extra Strength bottle.
For the current strength, apoaequorin amount, other ingredients, and directions, read the Supplement Facts panel on the exact package you are considering. This matters if you organize pills for yourself or someone you care for.
What does the apoaequorin research say?
A 2024 clinical review describes apoaequorin as a calcium-binding protein. It summarizes a company-funded, placebo-controlled study in which 218 people ages 40 to 95 took 10 mg daily or placebo for up to 90 days. The main comparison across all participants was not statistically significant. A later analysis of 97 participants with mild self-reported concerns found differences in verbal-learning and delayed-recall tests. The review also notes questions about how an oral protein is absorbed and reaches the brain. Read the full clinical review for its discussion of the study design and findings.
That gives you a sensible timeline to ask about: the published trial ran for 90 days. It does not give a dependable day-by-day answer for when one person will notice a change.
What has the FTC said about Prevagen memory claims?
The Federal Trade Commission said in December 2024 that a court ordered Quincy Bioscience to stop making the deceptive claims challenged in its lawsuit. The FTC said those claims misled people concerned about memory loss. More broadly, FTC guidance says health-product advertising should be truthful, not misleading, and supported by competent and reliable scientific evidence.
What side effects and safety questions should you consider?
In the 90-day apoaequorin study summarized in the clinical review, no serious adverse events were reported. One participant taking apoaequorin left the study after feeling irritable. That short study is not a substitute for your own medication and supplement review.
Bring the bottle or a clear photo of its label to your pharmacist if you take medicines or several supplements. Ask a clinician before starting any new supplement if you are pregnant, under 18, or have scheduled surgery. For a simple home record, write down the product name, dose, start date, every pill and supplement you take, and any new symptom. Keep it beside your medication list.
Ask for a provider appointment soon if memory changes are causing repeated questions, getting lost in familiar places, confusion about time or place, missed pills, unsafe cooking, or other safety-at-home problems. The National Institute on Aging identifies these changes as reasons to talk with a doctor.
What does Prevagen cost, and what is its refund policy?
Prevagen prices were not displayed in the captured brand material on October 7, 2026, so check the retailer or checkout for today’s price before ordering. Prevagen says orders over $50 may qualify for free shipping and that Subscribe and Save is available.
Its returns page says a customer may request a refund of the purchase price, including taxes and shipping charges, within 45 days of purchase. You need an original receipt and bottle with unused product, and the item must come from an authorized reseller. Prevagen says phone-processed refunds can take 6 to 8 weeks.
How does MemoFix compare on disclosed ingredients and price?
Use three plain criteria: disclosed amounts, cost per daily serving, and return terms. MemoFix is one option with amounts listed for every featured ingredient. Its seller says to take two capsules daily with water, 20 to 30 minutes before a meal, and markets the formula for memory and concentration. Check the current price or order through the Product Page.
| Criterion | Prevagen | MemoFix |
|---|---|---|
| Featured ingredients shown here | Apoaequorin; the archived Professional label listed 40 mg per capsule. | BCAAs 540 mg, bacopa extract 200 mg, rhodiola extract 100 mg, L-theanine 100 mg, and Panax ginseng extract 90 mg per two capsules. |
| Price per daily serving | Check the current package price and serving directions. | $2.63 with two bottles, $2.30 with three, or $1.63 with six. |
| Return window | 45 days, with receipt and original bottle requirements. | 60 days; the seller says bottles must be returned. |
MemoFix’s seller listed these prices on October 7, 2026: $79 per bottle in a two-bottle order plus $9.99 shipping; $69 per bottle for three; and $49 per bottle for six. The three- and six-bottle offers listed free shipping. Each bottle has 30 daily servings, which is how the per-serving figures above were calculated.
What does research say about the MemoFix ingredients?
MemoFix’s label makes comparison easier because it gives amounts. A bacopa systematic review examined six 12-week trials using 300 to 450 mg daily of different extracts. It found some evidence for free recall, while results in other cognitive areas were limited. MemoFix lists 200 mg of bacopa extract per daily serving, so it is not the same formula or dose as those trials.
Reviews of rhodiola describe research on life stress and fatigue. A 2025 review of L-theanine trials found small, uncertain differences in selected cognition and mood outcomes; some findings involved theanine combined with caffeine. MemoFix lists 100 mg L-theanine without caffeine. The NCCIH ginseng guide says Asian ginseng research has generally been small and short, and it may interact with medicines or affect blood clotting. These ingredient studies do not answer how the finished MemoFix combination will work for you.
What can you do today for poor memory or brain fog?
Start with a one-week memory-and-pills log. Each day, note sleep, meals, alcohol, new supplements, prescription timing, and any confusion or missed dose. Bring that list to a pharmacist or provider. The National Institute on Aging also recommends routines, calendars and notes, keeping keys and glasses in the same place, enough sleep, physical activity, and managing blood pressure and other ongoing health concerns.
If you are deciding whether to add a supplement, our supplement decision guide can help you prepare your questions. For day-to-day safety at home, see home prevention steps.
Before you order
- Confirm the exact Prevagen strength and full Supplement Facts panel on the package.
- Compare the final checkout total, shipping, and return steps.
- Ask your pharmacist to check your complete pills and supplements list for interactions.
- Keep the receipt, bottle, and a copy of the return terms.
By MercyAssistedCare.org Editorial Team